Identifying Potential Polymicrobial Pathogens Moving Beyond Differential Abundance to Driver Taxa

• Published in: Microbial ecology Vol. 80; no. 2; pp. 447 - 458
• Main Authors: Lu, Jiaqi, Zhang, Xuechen, Qiu, Qiongfen, Chen, Jiong, Xiong, Jinbo
• Format: Journal Article
• Language: English
• Published: New York Springer Science + Business Media 01.08.2020; Springer US; Springer Nature B.V
• Subjects: Abundance; Actinobacteria - isolation & purification; Actinobacteria - physiology; Aetiology; algorithms; amino acid metabolism; Amino acids; Animal diseases; Animals; Aquaculture; Aquatic animals; Bacteria - isolation & purification; Biomedical and Life Sciences; China; Cohorts; Commensals; Data processing; Disease; disease susceptibility; Diseases; Ecology; Energy metabolism; Etiology; feces; Gastrointestinal Microbiome; Geoecology/Natural Processes; health status; HOST MICROBE INTERACTIONS; Identification; Information processing; Intestinal microflora; intestinal microorganisms; Life Sciences; Lipid metabolism; Lipids; Metabolism; Microbial Ecology; Microbiology; Nature Conservation; Pathogens; Penaeidae - microbiology; Polyketides; Probiotics; Profiles; Ruegeria lacuscaerulensis; Shellfish; shrimp; Shrimps; Terpenes; terpenoids; Vibrio - physiology; Vibrio fluvialis; Vibrio tubiashii; Water Quality/Water Pollution; Waterborne diseases; China; Gut microbiota; Driver taxa; Polymicrobial pathogens; Shrimp disease; Primary colonizer

It is now recognized that some diseases of aquatic animals are attributed to polymicrobial pathogens infection. Thus, the traditional view of “one pathogen, one disease” might mislead the identification of multiple pathogens, which in turn impedes the design of probiotics. To address this gap, we ex...