Aberrant Functional Connectivity of Basal Forebrain Subregions with Cholinergic System in Short-term and Chronic Insomnia Disorder

• Published in: Journal of affective disorders Vol. 278; pp. 481 - 487
• Main Authors: Ma, Xiaofen, Fu, Shishun, Yin, Yi, Wu, Yunfan, Wang, Tianyue, Xu, Guang, Liu, Mengchen, Xu, Yikai, Tian, Junzhang, Jiang, Guihua
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.01.2021
• Subjects: Basal Forebrain - diagnostic imaging; Basal Forebrain Subregions; Cholinergic Agents; Chronic Insomnia Disorder; Functional Connectivity; Gray Matter; Humans; Magnetic Resonance Imaging; Psychiatric/Mental Health; Short-term Insomnia Disorder; Sleep Initiation and Maintenance Disorders - diagnostic imaging; Chronic Insomnia Disorder; Basal Forebrain Subregions; Functional Connectivity; Short-term Insomnia Disorder

•Short-term and chronic insomnia are two subtypes of insomnia.•Aberrant functional connectivity pattern of basal forebrain Ch_4 subregion in both two subtypes.•Middle frontal gyrus FC with Ch_4 was significantly correlated with ESS scores in Short-term subtype. To systematically investigate structur...