Urinary N-acetyl-β-d-Glucosaminidase Levels are Positively Correlated With 2-Hr Plasma Glucose Levels During Oral Glucose Tolerance Testing in Prediabetes

• Published in: Journal of clinical laboratory analysis Vol. 26; no. 6; pp. 473 - 480
• Main Authors: Ouchi, Motoshi, Suzuki, Tatsuya, Hashimoto, Masao, Motoyama, Masayuki, Ohara, Makoto, Suzuki, Kazunari, Igari, Yoshimasa, Watanabe, Kentaro, Nakano, Hiroshi, Oba, Kenzo
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.11.2012; John Wiley and Sons Inc
• Subjects: Acetylglucosaminidase - urine; Adolescent; Adult; Aged; Blood Glucose - metabolism; cystatin C; Cystatin C - blood; diabetic nephropathy; Female; Glucose Tolerance Test; Glycated Hemoglobin A - metabolism; Humans; impaired glucose tolerance; Linear Models; Male; Middle Aged; N-acetyl-β-d-glucosaminidase; Prediabetic State - blood; Prediabetic State - urine; Statistics, Nonparametric; tubular dysfunction

Background Urinary N‐acetyl‐β‐D‐glucosaminidase (NAG) excretion is increased in patients with impaired glucose tolerance (IGT). This study investigated when during the oral glucose tolerance test (OGTT) the plasma glucose, urine glucose, and insulin levels correlate most strongly with urinary N‐acet...