Synthesizing Subject-matter Expertise for Variable Selection in Causal Effect Estimation: A Case Study

• Published in: Epidemiology (Cambridge, Mass.) Vol. 35; no. 5; p. 642
• Main Authors: Debertin, Julia, Jurado Vélez, Javier A, Corlin, Laura, Hidalgo, Bertha, Murray, Eleanor J
• Format: Journal Article
• Language: English
• Published: United States 01.09.2024
• Subjects: Causality; Data Interpretation, Statistical; Female; Humans; Male; Middle Aged; Placebos; Randomized Controlled Trials as Topic

Causal graphs are an important tool for covariate selection but there is limited applied research on how best to create them. Here, we used data from the Coronary Drug Project trial to assess a range of approaches to directed acyclic graph (DAG) creation. We focused on the effect of adherence on mor...