Determination of mouse skeletal muscle architecture using three-dimensional diffusion tensor imaging

• Published in: Magnetic resonance in medicine Vol. 53; no. 6; pp. 1333 - 1340
• Main Authors: Heemskerk, Anneriet M., Strijkers, Gustav J., Vilanova, Anna, Drost, Maarten R., Nicolay, Klaas
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.06.2005
• Subjects: Animals; Diffusion Magnetic Resonance Imaging - methods; diffusion tensor imaging; Electric Stimulation; exercise-induced T2 enhancement; Feasibility Studies; fiber tracking; Hindlimb; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Mice; Mice, Inbred C57BL; muscle fiber architecture; Muscle, Skeletal - physiology

Muscle architecture is the main determinant of the mechanical behavior of skeletal muscles. This study explored the feasibility of diffusion tensor imaging (DTI) and fiber tracking to noninvasively determine the in vivo three‐dimensional (3D) architecture of skeletal muscle in mouse hind leg. In six...