Unwrapping new layers of complexity in axon/glial relationships

• Published in: Glia Vol. 29; no. 2; pp. 112 - 117
• Main Authors: Witt, Andrea, Brady, Scott T.
• Format: Journal Article
• Language: English
• Published: New York John Wiley & Sons, Inc 15.01.2000
• Subjects: Animals; Axons - metabolism; Central Nervous System - cytology; Central Nervous System - metabolism; Cytoskeleton - genetics; Cytoskeleton - metabolism; Gene Expression - physiology; Humans; Life Sciences (General); Mice; Mice, Neurologic Mutants; Myelin Sheath - metabolism; Myelin Sheath - physiology; Neuroglia - cytology; Neuroglia - metabolism; saltatory conduction; Schwann Cells - cytology; Schwann Cells - physiology; Space life sciences; Non-Nasa Center; Nasa Discipline Neuroscience; Review; Review, Tutorial; NASA Discipline Neuroscience; Non-NASA Center

Traditionally, myelin has been portrayed as merely playing structural and supportive roles in the nervous system, providing the "insulation" that allows saltatory conduction of the action potential. In 1979, Aguayo and colleagues demonstrated that the axon diameter changes locally in the a...