Intramyocellular Lipid Content in Human Skeletal Muscle

• Published in: Obesity (Silver Spring, Md.) Vol. 14; no. 3; pp. 357 - 367
• Main Authors: Schrauwen‐Hinderling, Vera B., Hesselink, Matthijs K.C., Schrauwen, Patrick, Kooi, Marianne Eline
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.03.2006
• Subjects: Biopsy; Body fat; Dietary Fats - metabolism; Energy; Exercise; Exercise - physiology; Fatty acids; Fatty Acids - blood; Humans; Insulin resistance; Insulin Resistance - physiology; Lipid Metabolism - physiology; Lipids; Lipids - analysis; Localization; Magnetic resonance imaging; Methods; Microscopy; Mitochondria; Morphology; Muscle Fibers, Skeletal - metabolism; Muscle, Skeletal - metabolism; Musculoskeletal system; Oxidation; Physical Endurance - physiology; Physical fitness; Physiology; Spectrum analysis; Tomography; Netherlands

Fat can be stored not only in adipose tissue but also in other tissues such as skeletal muscle. Fat droplets accumulated in skeletal muscle [intramyocellular lipids (IMCLs)] can be quantified by different methods, all with advantages and drawbacks. Here, we briefly review IMCL quantification methods...