Intramyocellular Lipid Content in Human Skeletal Muscle

Fat can be stored not only in adipose tissue but also in other tissues such as skeletal muscle. Fat droplets accumulated in skeletal muscle [intramyocellular lipids (IMCLs)] can be quantified by different methods, all with advantages and drawbacks. Here, we briefly review IMCL quantification methods...

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Bibliographic Details
Published inObesity (Silver Spring, Md.) Vol. 14; no. 3; pp. 357 - 367
Main Authors Schrauwen‐Hinderling, Vera B., Hesselink, Matthijs K.C., Schrauwen, Patrick, Kooi, Marianne Eline
Format Journal Article
LanguageEnglish
Published Oxford, UK Blackwell Publishing Ltd 01.03.2006
Subjects
Biopsy
Body fat
Dietary Fats - metabolism
Energy
Exercise
Exercise - physiology
Fatty acids
Fatty Acids - blood
Humans
Insulin resistance
Insulin Resistance - physiology
Lipid Metabolism - physiology
Lipids
Lipids - analysis
Localization
Magnetic resonance imaging
Methods
Microscopy
Mitochondria
Morphology
Muscle Fibers, Skeletal - metabolism
Muscle, Skeletal - metabolism
Musculoskeletal system
Oxidation
Physical Endurance - physiology
Physical fitness
Physiology
Spectrum analysis
Tomography
Netherlands
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Summary:Fat can be stored not only in adipose tissue but also in other tissues such as skeletal muscle. Fat droplets accumulated in skeletal muscle [intramyocellular lipids (IMCLs)] can be quantified by different methods, all with advantages and drawbacks. Here, we briefly review IMCL quantification methods that use biopsy specimens (biochemical quantification, electron microscopy, and histochemistry) and non‐invasive alternatives (magnetic resonance spectroscopy, magnetic resonance imaging, and computed tomography).
Bibliography:The costs of publication of this article were defrayed, in part, by the payment of page charges. This article must, therefore, be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
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ISSN:1930-7381
1930-739X
DOI:10.1038/oby.2006.47