Impaired Oxygen Utilization in Skeletal Muscle of CRPS I Patients

• Published in: The Journal of surgical research Vol. 173; no. 1; pp. 145 - 152
• Main Authors: Tan, Edward C.T.H., Ter Laak, Henk J., Hopman, M.T.E., van Goor, H., Goris, R. Jan A.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.03.2012
• Subjects: Adolescent; Adult; Amputation; Basement Membrane - ultrastructure; Capillaries - pathology; Capillaries - ultrastructure; Chronic Disease; complex regional pain syndrome; Female; Humans; Leg - surgery; Male; Middle Aged; Muscle Fibers, Skeletal - metabolism; Muscle Fibers, Skeletal - pathology; Muscle Fibers, Skeletal - ultrastructure; Muscle, Skeletal - blood supply; Muscle, Skeletal - metabolism; Muscle, Skeletal - pathology; Oxygen - metabolism; oxygen extraction; Reflex Sympathetic Dystrophy - metabolism; Reflex Sympathetic Dystrophy - pathology; skeletal muscle; Surgery; Young Adult; oxygen metabolism; amputation; complex regional pain syndrome; skeletal muscle; oxygen extraction

The purpose of this study was to evaluate oxygen extraction and utilization in end stage chronic complex regional pain syndrome type I (CRPS I) patients undergoing amputation and to relate these to muscle histology of the amputated limb. In 25 patients with severe CRPS I requiring amputation of the...