Dopamine D4 and D5 receptor gene variant effects on clozapine response in schizophrenia: Replication and exploration - Hwang, Rudi; Tiwari, Arun K.; Zai, Clement C.; Felsky, Daniel; Remington, Eli; Wallace, Tessa; Tong, Ryan P.; Souza, Renan P.; Oh, Gabriel; Potkin, Steven G.; Lieberman, Jeffrey A.; Meltzer, Herbert Y.; et al. (Progress in neuro-psychopharmacology & biological psychiatry, 2012)
Keywords: African Continental Ancestry Group - genetics; Antipsychotic; Antipsychotic Agents - therapeutic use; Clozapine; Clozapine - therapeutic use; Dopamine D4 receptor gene (DRD4); Dopamine D4 receptors; Dopamine D5 receptor gene (DRD5); Dopamine D5 receptors; European Continental Ancestry Group - genetics; Exons; Exploration; Female; Gene polymorphism; Genetic Variation - genetics; Genotyping; Humans; Introns; Male; Mental disorders; Microsatellites; Neuroleptics; Pharmacogenetics; Polymorphism, Single Nucleotide - genetics; Prospective Studies; Receptors, Dopamine D4 - genetics; Receptors, Dopamine D5 - genetics; Replication; Response; Schizophrenia; Schizophrenia - drug therapy; Schizophrenia - ethnology; Schizophrenia - genetics; Single-nucleotide polymorphism; Statistics; Treatment Outcome; ADHD; Dopamine D5 receptor gene (DRD5); ABI; dNTP; mRNA; SCZ; cAMP; PFC; bp; (2–8)R; BPRS; CLZ; ANCOVA; YRI; DRD(1–5); SNP; Sp1; Antipsychotic; DSM; IHMP; Pharmacogenetics; OR; d; CAMH; NEB; Clozapine; BPOS; AP; Response; BNEG; D(1–5); CEU; DNA; Dopamine D4 receptor gene (DRD4); LD; DA; PCR