Macrophage Migration Inhibitory Factor Is a Novel Determinant of Cigarette Smoke–Induced Lung Damage - Fallica, Jonathan; Boyer, Laurent; Kim, Bo; Serebreni, Leonid; Varela, Lidenys; Hamdan, Omar; Wang, Lan; Simms, Tiffany; Damarla, Mahendra; Kolb, Todd M.; Bucala, Richard; Mitzner, Wayne; et al. (American journal of respiratory cell and molecular biology, 2014)
Keywords: Animals; Apoptosis; Apoptosis - drug effects; Blotting, Western; Deoxyribonucleic acid; Disease; DNA; DNA Damage - drug effects; Endothelial Cells - drug effects; Endothelial Cells - pathology; Gene expression; Homeostasis; Humans; Hypoxia; Immunoenzyme Techniques; Inflammation - etiology; Inflammation - metabolism; Inflammation - pathology; Intramolecular Oxidoreductases - physiology; Kinases; Lung - drug effects; Lung - metabolism; Lung - pathology; Macrophage Migration-Inhibitory Factors - physiology; Methods; Mice; Mice, Inbred C57BL; Mice, Knockout; Original Research; Oxidative Stress; Pulmonary Disease, Chronic Obstructive - etiology; Pulmonary Disease, Chronic Obstructive - metabolism; Pulmonary Disease, Chronic Obstructive - pathology; Pulmonary Emphysema - etiology; Pulmonary Emphysema - metabolism; Pulmonary Emphysema - pathology; Smoke - adverse effects; Studies; Transcription factors; Tumor Suppressor Protein p53 - metabolism; apoptosis; cigarette; macrophage migration inhibitory factor; endothelial; emphysema