Bilateral thalamic gray matter changes in patients with restless legs syndrome

• Published in: NeuroImage (Orlando, Fla.) Vol. 24; no. 4; pp. 1242 - 1247
• Main Authors: Etgen, Thorleif, Draganski, Bogdan, Ilg, Carolin, Schröder, Michael, Geisler, Peter, Hajak, Göran, Eisensehr, Ilonka, Sander, Dirk, May, Arne
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.02.2005; Elsevier Limited
• Subjects: Adult; Age; Aged; Dopamine; Family medical history; Female; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; MRI; NMR; Nuclear magnetic resonance; Patients; Pulvinar; Reproducibility of Results; Restless legs; Restless legs syndrome; Restless Legs Syndrome - pathology; Studies; Thalamus; Thalamus - pathology; Voxel based morphometry; Womens health; Thalamus; Voxel based morphometry; MRI; Restless legs; Pulvinar

Restless legs syndrome (RLS) is a common neurological disorder of a primary unpleasant sensation with an urge to move the legs occurring at rest. The etiology of idiopathic RLS is unknown and structural cerebral abnormalities have so far not been detected. We studied 51 right-handed patients with an...