Hyaluronic Acid-Poly-D-Lysine-Based Three-Dimensional Hydrogel for Traumatic Brain Injury

• Published in: Tissue engineering Vol. 11; no. 3-4; pp. 513 - 525
• Main Authors: Tian, W.M., Hou, S.P., Ma, J., Zhang, C.L., Xu, Q.Y., Lee, I.S., Li, H.D., Spector, M., Cui, F.Z.
• Format: Journal Article
• Language: English
• Published: United States Mary Ann Liebert, Inc 01.03.2005
• Subjects: Animals; Animals, Newborn; Biocompatible Materials - chemistry; Brain Injuries - pathology; Brain Injuries - therapy; Cell Proliferation; Cells, Cultured; Guided Tissue Regeneration - methods; Hyaluronic Acid - chemistry; Hydrogels - chemistry; Materials Testing; Molecular Conformation; Nerve Regeneration - physiology; Neurons - cytology; Neurons - physiology; Polylysine - chemistry; Porosity; Rats; Rats, Sprague-Dawley; Rats, Wistar; Surface Properties; Tissue Engineering - methods; Treatment Outcome

Brain tissue engineering in the postinjury brain represents a promising option for cellular replacement and rescue, providing a cell scaffold for either transplanted or resident cells. In this article, a hyaluronic acid (HA)-poly-D-lysine (PDL) copolymer hydrogel with an open porous structure and vi...