The potential role of echocardiographic strain imaging for evaluating cardiotoxicity due to cancer therapy

• Published in: Heart, lung & circulation Vol. 20; no. 1; pp. 3 - 9
• Main Authors: Stoodley, Paul W., Richards, David A.B., Meikle, Steve R., Clarke, Jillian, Hui, Rina, Thomas, Liza
• Format: Journal Article
• Language: English
• Published: Australia Elsevier B.V 01.01.2011
• Subjects: Anthracyclines; Anticarcinogenic Agents - administration & dosage; Anticarcinogenic Agents - adverse effects; Asymptomatic Diseases; Cardiotoxicity; Cardiotoxins; Cardiovascular; Clinical Trials as Topic; Early Diagnosis; Echocardiography; Echocardiography - methods; Echocardiography - trends; Heart Diseases - chemically induced; Heart Diseases - diagnosis; Heart Diseases - physiopathology; Heart Diseases - prevention & control; Image Enhancement; Left ventricular ejection fraction (LVEF); Monitoring, Physiologic; Neoplasms - drug therapy; Strain; Strain rate; Trastuzumab; Left ventricular ejection fraction (LVEF); Anthracyclines; Echocardiography; Cardiotoxicity; Trastuzumab; Strain; Strain rate

Refinements to conventional treatment and the development of new therapies have led to significant improvements in cancer survival. Yet, many frontline cancer treatments continue to be hindered by their significant side effects, amongst which cardiotoxicity is particularly important. Therefore, the...