Dihydroartemisinin Regulated the MMP-Mediated Cellular Microenvironment to Alleviate Rheumatoid Arthritis

• Published in: Research (Washington) Vol. 7; p. 0459
• Main Authors: Guo, Qiuyan, Wang, Qixin, Chen, Jiayun, Zhao, Minghong, Lu, Tianming, Guo, Zuchang, Wang, Chen, Wong, Yin Kwan, He, Xueling, Chen, Lin, Zhang, Wenjing, Dai, Chuanhao, Shen, Shengnan, Pang, Huanhuan, Xia, Fei, Qiu, Chong, Xie, Daoyuan, Wang, Jigang
• Format: Journal Article
• Language: English
• Published: United States AAAS 01.01.2024; American Association for the Advancement of Science (AAAS)
• Subjects: Health Science

Rheumatoid arthritis (RA) is an autoimmune disease with features of synovial inflammation, cartilage erosion, bone destruction, and pain and is currently lacking a satisfactory treatment strategy. Dihydroartemisinin (DHA), the active metabolite of artemisinin, has exhibited outstanding suppressive e...