Cancer risks in Crohn disease patients

• Published in: Annals of oncology Vol. 20; no. 3; pp. 574 - 580
• Main Authors: Hemminki, K., Li, X., Sundquist, J., Sundquist, K.
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.03.2009; Oxford Publishing Limited (England)
• Subjects: age at onset; Antineoplastic agents; autoimmunity; Biological and medical sciences; cancer risk; Crohn Disease - complications; Crohn Disease - epidemiology; Epidemiology; Gastroenterology. Liver. Pancreas. Abdomen; Humans; Incidence; inflammatory bowel disease; Medical sciences; Neoplasms - complications; Neoplasms - epidemiology; Other diseases. Semiology; Pharmacology. Drug treatments; Registries; Risk Factors; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus; subsequent cancer; Sweden - epidemiology; Tumors; Sweden; Europe; cancer risk; autoimmunity; age at onset; inflammatory bowel disease; subsequent cancer; Autoimmunity; Human; Patient; Malignant tumor; Inflammatory disease; Crohn disease; Age of onset; Second cancer; Risk factor; Digestive diseases; Intestinal disease; Cancer; Ulcerative colitis

Background: Patients diagnosed with Crohn disease (CD) are known to be at an increased risk of bowel cancers and lymphoma. CD is an autoimmune disease and we hypothesize that the patients are predisposed to a wider spectrum of cancers. Patients and methods: A CD research database was constructed by...