The effect of template choice on morphometric analysis of pediatric brain data

• Published in: NeuroImage (Orlando, Fla.) Vol. 45; no. 3; pp. 769 - 777
• Main Authors: Yoon, Uicheul, Fonov, Vladimir S., Perusse, Daniel, Evans, Alan C.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.04.2009; Elsevier Limited
• Subjects: Adult; Age; Brain; Brain - anatomy & histology; Brain Mapping - methods; Child; Cortical surface; Female; Females; Humans; Image Interpretation, Computer-Assisted - methods; Magnetic Resonance Imaging; Male; Parcellation; Pediatric brain template; Pediatrics; Pediatrics - methods; Population; Spatial normalization; Tissue classification; Twin Studies as Topic; Spatial normalization; Cortical surface; Tissue classification; Magnetic resonance imaging; Parcellation; Pediatric brain template
• ISSN: 1053-8119; 1095-9572; 1095-9572
• DOI: 10.1016/j.neuroimage.2008.12.046

The present study investigated the “template effect” on the morphometric analysis of a pediatric brain MRI database obtained from 8-year-old children through various measures of surface and volumetric morphologies. We first constructed an age-appropriate template from an independent set of pediatric...