Refractive error and monochromatic aberrations in Singaporean children

Higher order optical aberrations were measured in 273 cyclopleged Singaporean school children using a Bausch and Lomb Zywave aberrometer, with 268 of these subjects also undergoing corneal topography measurements (Tomey TMS 2 system). Subjects with low myopia (>−3.00 to −0.50 D) showed slightly,...

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Published in	Vision research (Oxford) Vol. 42; no. 14; pp. 1809 - 1824
Main Authors	Carkeet, Andrew, Dong Luo, Hai, Tong, Louis, Mei Saw, Seang, Tan, Donald T.H
Format	Journal Article
Language	English
Published	Oxford Elsevier Ltd 01.06.2002 Elsevier Science
Subjects	Aberration Biological and medical sciences Child Children Cornea Cornea - physiopathology Corneal Topography Female Humans Lens, Crystalline - physiopathology Male Medical sciences Myopia - ethnology Myopia - etiology Myopia - physiopathology Ophthalmology Optics and Photonics Refraction Refractive Errors - ethnology Refractive Errors - physiopathology Sensory Deprivation Topography Vision disorders Asia Singapore Cornea Aberration Children Refraction Topography Human Measurement Eye disease School age Vision disorder Chromatic aberration Refractive error Diagnosis Child
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ISSN	0042-6989 1878-5646
DOI	10.1016/S0042-6989(02)00114-1

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Abstract	Higher order optical aberrations were measured in 273 cyclopleged Singaporean school children using a Bausch and Lomb Zywave aberrometer, with 268 of these subjects also undergoing corneal topography measurements (Tomey TMS 2 system). Subjects with low myopia (>−3.00 to −0.50 D) showed slightly, but significantly, less positive levels of spherical aberration than other refractive error groups. Chinese subjects also showed significantly higher amounts of aberrations than Malay subjects, particularly for vertical coma, but also for horizontal coma and spherical aberration. Anterior corneal spherical aberration (calculated from topography) was significantly correlated with whole eye spherical aberration, but did not vary significantly with refractive error or racial background. Residual spherical aberration (i.e. of posterior cornea and crystalline lens) did vary significantly with refractive error and race. Our results do not provide any evidence for aberration-driven form-deprivation as a major mechanism of myopia development.
AbstractList	Higher order optical aberrations were measured in 273 cyclopleged Singaporean school children using a Bausch and Lomb Zywave aberrometer, with 268 of these subjects also undergoing corneal topography measurements (Tomey TMS 2 system). Subjects with low myopia (> -3.00 to -0.50 D) showed slightly, but significantly, less positive levels of spherical aberration than other refractive error groups. Chinese subjects also showed significantly higher amounts of aberrations than Malay subjects, particularly for vertical coma, but also for horizontal coma and spherical aberration. Anterior corneal spherical aberration (calculated from topography) was significantly correlated with whole eye spherical aberration, but did not vary significantly with refractive error or racial background. Residual spherical aberration (i.e. of posterior cornea and crystalline lens) did vary significantly with refractive error and race. Our results do not provide any evidence for aberration-driven form-deprivation as a major mechanism of myopia development. Higher order optical aberrations were measured in 273 cyclopleged Singaporean school children using a Bausch and Lomb Zywave aberrometer, with 268 of these subjects also undergoing corneal topography measurements (Tomey TMS 2 system). Subjects with low myopia (>−3.00 to −0.50 D) showed slightly, but significantly, less positive levels of spherical aberration than other refractive error groups. Chinese subjects also showed significantly higher amounts of aberrations than Malay subjects, particularly for vertical coma, but also for horizontal coma and spherical aberration. Anterior corneal spherical aberration (calculated from topography) was significantly correlated with whole eye spherical aberration, but did not vary significantly with refractive error or racial background. Residual spherical aberration (i.e. of posterior cornea and crystalline lens) did vary significantly with refractive error and race. Our results do not provide any evidence for aberration-driven form-deprivation as a major mechanism of myopia development. Higher order optical aberrations were measured in 273 cyclopleged Singaporean school children using a Bausch and Lomb Zywave aberrometer, with 268 of these subjects also undergoing corneal topography measurements (Tomey TMS 2 system). Subjects with low myopia (> -3.00 to -0.50 D) showed slightly, but significantly, less positive levels of spherical aberration than other refractive error groups. Chinese subjects also showed significantly higher amounts of aberrations than Malay subjects, particularly for vertical coma, but also for horizontal coma and spherical aberration. Anterior corneal spherical aberration (calculated from topography) was significantly correlated with whole eye spherical aberration, but did not vary significantly with refractive error or racial background. Residual spherical aberration (i.e. of posterior cornea and crystalline lens) did vary significantly with refractive error and race. Our results do not provide any evidence for aberration-driven form-deprivation as a major mechanism of myopia development.Higher order optical aberrations were measured in 273 cyclopleged Singaporean school children using a Bausch and Lomb Zywave aberrometer, with 268 of these subjects also undergoing corneal topography measurements (Tomey TMS 2 system). Subjects with low myopia (> -3.00 to -0.50 D) showed slightly, but significantly, less positive levels of spherical aberration than other refractive error groups. Chinese subjects also showed significantly higher amounts of aberrations than Malay subjects, particularly for vertical coma, but also for horizontal coma and spherical aberration. Anterior corneal spherical aberration (calculated from topography) was significantly correlated with whole eye spherical aberration, but did not vary significantly with refractive error or racial background. Residual spherical aberration (i.e. of posterior cornea and crystalline lens) did vary significantly with refractive error and race. Our results do not provide any evidence for aberration-driven form-deprivation as a major mechanism of myopia development.
Author	Mei Saw, Seang Dong Luo, Hai Tan, Donald T.H Carkeet, Andrew Tong, Louis
Author_xml	– sequence: 1 givenname: Andrew surname: Carkeet fullname: Carkeet, Andrew email: seri_acarkeet@snec.com.sg organization: Singapore National Eye Centre, Singapore Eye Research Institute, Level 6, 11 Third Hospital Avenue, 168751 Singapore – sequence: 2 givenname: Hai surname: Dong Luo fullname: Dong Luo, Hai organization: Department of Community, Occupational and Family Medicine, National University of Singapore, 16 Medical Drive, 117597 Singapore – sequence: 3 givenname: Louis surname: Tong fullname: Tong, Louis organization: Singapore National Eye Centre, 11 Third Hospital Avenue, 168751 Singapore – sequence: 4 givenname: Seang surname: Mei Saw fullname: Mei Saw, Seang organization: Department of Community, Occupational and Family Medicine, National University of Singapore, 16 Medical Drive, 117597 Singapore – sequence: 5 givenname: Donald T.H surname: Tan fullname: Tan, Donald T.H organization: Singapore National Eye Centre, Singapore Eye Research Institute, Level 6, 11 Third Hospital Avenue, 168751 Singapore
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Keywords	Cornea Aberration Children Refraction Topography Human Measurement Eye disease School age Vision disorder Chromatic aberration Refractive error Diagnosis Child
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can we do better than nature publication-title: Journal of Refractive Surgery doi: 10.3928/1081-597X-20000901-10
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Snippet	Higher order optical aberrations were measured in 273 cyclopleged Singaporean school children using a Bausch and Lomb Zywave aberrometer, with 268 of these...
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SubjectTerms	Aberration Biological and medical sciences Child Children Cornea Cornea - physiopathology Corneal Topography Female Humans Lens, Crystalline - physiopathology Male Medical sciences Myopia - ethnology Myopia - etiology Myopia - physiopathology Ophthalmology Optics and Photonics Refraction Refractive Errors - ethnology Refractive Errors - physiopathology Sensory Deprivation Topography Vision disorders
Title	Refractive error and monochromatic aberrations in Singaporean children
URI	https://dx.doi.org/10.1016/S0042-6989(02)00114-1 https://www.ncbi.nlm.nih.gov/pubmed/12127112 https://www.proquest.com/docview/71942535
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