Circulating high-molecular-weight RAGE ligands activate pathways implicated in the development of diabetic nephropathy - Penfold, Sally A.; Coughlan, Melinda T.; Patel, Sheila K.; Srivastava, Piyush M.; Sourris, Karly C.; Steer, David; Webster, Diane E.; Thomas, Merlin C.; MacIsaac, Richard J.; Jerums, George; Burrell, Louise M.; Cooper, Mark E.; et al. (Kidney international, 2010)
Keywords: advanced glycation end product; Aged; Antibodies, Neutralizing - metabolism; Associated diseases and complications; Biological and medical sciences; Case-Control Studies; Diabetes Mellitus, Type 2 - blood; Diabetes. Impaired glucose tolerance; Diabetic Nephropathies - blood; Diabetic Nephropathies - metabolism; diabetic nephropathy; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Enzyme-Linked Immunosorbent Assay; Female; high-mobility group box 1; HMGB1 Protein - analysis; HMGB1 Protein - metabolism; Humans; Kidneys; Ligands; Lysine - analogs & derivatives; Lysine - analysis; Lysine - metabolism; Male; Medical sciences; Middle Aged; Molecular Weight; Nephrology. Urinary tract diseases; Protein Kinase C-alpha - metabolism; RAGE; Receptor for Advanced Glycation End Products; Receptors, Immunologic - metabolism; Transcription, Genetic; Urinary system involvement in other diseases. Miscellaneous; advanced glycation end product; high-mobility group box 1; RAGE; diabetic nephropathy; Endocrinopathy; Kidney disease; Nephrology; Urinary system disease; Ligand; Diabetes mellitus; Mobility; Urology; Concomitant disease; Advanced glycation end products; High molecular weight; Receptor for advanced glycation endproducts; Development; Diabetic nephropathy