Pharmacokinetics and Pharmacodynamics of Cinacalcet in Hepatic Impairment: Phase I, Open-Label, Parallel-Group, Single-Dose, Single-Centre Study - Padhi, Desmond; Harris, Robert Z.; Salfi, Margaret; Noveck, Robert J.; Sullivan, John T. (Clinical drug investigation, 2008)
Keywords: Administration, Oral; Aged; Area Under Curve; Calcium - blood; Chromatography, High Pressure Liquid - methods; Cinacalcet Hydrochloride; Female; Half-Life; Headache - chemically induced; Humans; Immunoassay - methods; Internal Medicine; Liver - metabolism; Liver Diseases - blood; Liver Diseases - metabolism; Liver Diseases - physiopathology; Male; Mass Spectrometry - methods; Medicine; Medicine & Public Health; Metabolic Clearance Rate; Middle Aged; Naphthalenes - administration & dosage; Naphthalenes - adverse effects; Naphthalenes - pharmacokinetics; Nausea - chemically induced; Original Research Article; Pharmacology/Toxicology; Pharmacotherapy; Chronic Kidney Disease Patient; Secondary Hyperparathyroidism; Parathyroid Carcinoma; Cinacalcet; Hepatic Impairment