Hepatic Encephalopathy in Children With Acute Liver Failure: Utility of Serum Neuromarkers

• Published in: Journal of pediatric gastroenterology and nutrition Vol. 69; no. 1; pp. 108 - 115
• Main Authors: Toney, Nicole A, Bell, Michael J, Belle, Steven H, Hardison, Regina M, Rodriguez-Baez, Norberto, Loomes, Kathleen M, Vodovotz, Yoram, Zamora, Ruben, Squires, Robert H
• Format: Journal Article
• Language: English
• Published: United States by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology 01.07.2019

BACKGROUND:Pediatric acute liver failure (PALF) is a public heath burden, often requiring prolonged hospitalization and liver transplantation. Hepatic encephalopathy (HE) is a complication of PALF with limited diagnostic tools to predict outcomes. Serum neurological markers (neuron-specific enolase,...