TRPM7 silencing attenuates Mg2+ influx in cardiac myoblasts, H9c2 cells

• Published in: The journal of physiological sciences Vol. 70; no. 1; pp. 1 - 47
• Main Authors: Tashiro, Michiko, Konishi, Masato, Kobayashi, Ryo, Inoue, Hana, Yokoyama, Utako
• Format: Journal Article
• Language: English
• Published: Heidelberg Springer 07.10.2020; BioMed Central
• Subjects: Antibodies; Calcium; Efficiency; Ethylenediaminetetraacetic acid; Fluorescent indicators; Homeostasis; Magnesium; Myoblasts; Physiology; Scientific equipment and supplies industry; Short Communication; Transient receptor potential proteins; United States; United States > US

TRPM7, a member of the melastatin subfamily of transient receptor potential channels, is suggested to be a potential candidate for a physiological Mg 2+ channel. However, there is no direct evidence of Mg 2+ permeation through endogenous TRPM7. To determine the physiological roles of TRPM7 in intrac...