Engineered protein-iron oxide hybrid biomaterial for MRI-traceable drug encapsulation

• Published in: Molecular systems design & engineering Vol. 7; no. 8; pp. 915 - 932
• Main Authors: Hill, Lindsay K, Britton, Dustin, Jihad, Teeba, Punia, Kamia, Xie, Xuan, Delgado-Fukushima, Erika, Liu, Che Fu, Mishkit, Orin, Liu, Chengliang, Hu, Chunhua, Meleties, Michael, Renfrew, P. Douglas, Bonneau, Richard, Wadghiri, Youssef Z, Montclare, Jin Kim
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 01.08.2022; Royal Society of Chemistry (RSC)
• Subjects: Alkynes; Antibodies; Binding; Biocompatibility; Biomedical engineering; Biomedical materials; Coils; Cycloaddition; Doxorubicin; Encapsulation; Glycoproteins; Hydrogels; Iron oxides; Magnetic resonance imaging; Medical imaging; Nanofibers; Nanoparticles; Proteins; Scaffolds; Surgical implants; Tissue engineering; iron oxide; fiber; protein engineering; biomineralization; MRI; drug encapsulation

Labeled protein-based biomaterials have become popular for various biomedical applications such as tissue-engineered, therapeutic, and diagnostic scaffolds. Labeling of protein biomaterials, including with ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles, has enabled a wide variety of i...