Topological analysis as a tool for detection of abnormalities in protein–protein interaction data

• Published in: Bioinformatics Vol. 38; no. 16; pp. 3968 - 3975
• Main Authors: Nowakowska, Alicja W, Kotulska, Malgorzata
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 10.08.2022
• Subjects: Humans; Original Papers; Protein Interaction Maps; Software

Abstract Motivation Protein–protein interaction datasets, which can be modeled as networks, constitute an essential layer in multi-omics approach to biomedical knowledge. This representation gives insight into molecular pathways, help to uncover novel potential drug targets or predict a therapy outc...