Cell cycle disturbances and apoptosis induced by topotecan and gemcitabine on human lung cancer cell lines
Apoptosis is a major mode of cell death in response to cytotoxic drug treatment. A correlation between induction of apoptosis and chemosensitivity has been documented in some preclinical models. Topotecan (a topoisomerase I inhibitor) and gemcitabine (a deoxycytidine analogue), two active new drugs...
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Published in | European journal of cancer (1990) Vol. 35; no. 5; pp. 796 - 807 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Oxford
Elsevier Ltd
01.05.1999
Elsevier |
Subjects | |
Online Access | Get full text |
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