Atlas-based whole-body segmentation of mice from low-contrast Micro-CT data

• Published in: Medical image analysis Vol. 14; no. 6; pp. 723 - 737
• Main Authors: Baiker, Martin, Milles, Julien, Dijkstra, Jouke, Henning, Tobias D., Weber, Axel W., Que, Ivo, Kaijzel, Eric L., Löwik, Clemens W.G.M., Reiber, Johan H.C., Lelieveldt, Boudewijn P.F.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.12.2010
• Subjects: Animals; Articulated registration; Atlas-based whole-body segmentation; Computer Simulation; In vivo small animal imaging; Mice - anatomy & histology; Mice, Inbred BALB C; Micro-CT; Models, Anatomic; Radiographic Image Interpretation, Computer-Assisted - methods; Tomography, X-Ray Computed - methods; Tomography, X-Ray Computed - veterinary; Whole Body Imaging - methods; Micro-CT; Atlas-based whole-body segmentation; Articulated registration; In vivo small animal imaging

This paper presents a fully automated method for atlas-based whole-body segmentation in non-contrast-enhanced Micro-CT data of mice. The position and posture of mice in such studies may vary to a large extent, complicating data comparison in cross-sectional and follow-up studies. Moreover, Micro-CT...