The clinical utility and diagnostic implementation of human subject cell transdifferentiation followed by RNA sequencing - Li, Shenglan; Zhao, Sen; Sinson, Jefferson C.; Bajic, Aleksandar; Rosenfeld, Jill A.; Neeley, Matthew B.; Pena, Mezthly; Worley, Kim C.; Burrage, Lindsay C.; Weisz-Hubshman, Monika; Ketkar, Shamika; Craigen, William J.; et al. (American journal of human genetics, 2024)
Keywords: Cell Transdifferentiation - genetics; clinically accessible tissue; Female; fibroblast; Fibroblasts - cytology; Fibroblasts - metabolism; genetic diagnosis; Humans; induced neuron; isoform; Male; Nervous System Diseases - diagnosis; Nervous System Diseases - genetics; neurological disorder; Neurons - cytology; Neurons - metabolism; Reproducibility of Results; RNA sequencing; RNA-seq; RNA-Seq - methods; Sequence Analysis, RNA - methods; Transcriptome; transdifferentiation; RNA sequencing; clinically accessible tissue; fibroblast; RNA-seq; transcriptome; transdifferentiation; induced neuron; genetic diagnosis; isoform; neurological disorder