Association of polymorphism genes LPL, ADRB2, AGT and AGTR1 with risk of hyperinsulinism and insulin resistance in the Kazakh population

• Published in: Biomedical reports Vol. 13; no. 5; p. 1
• Main Authors: Shakhanova, Aizhan, Aukenov, Nurlan, Nurtazina, Alma, Massabayeva, Meruyert, Babenko, Dmitriy, Adiyeva, Madina, Shaimardonov, Nurlan
• Format: Journal Article
• Language: English
• Published: Athens Spandidos Publications 01.11.2020; Spandidos Publications UK Ltd; D.A. Spandidos
• Subjects: Adrenergic receptors; Angiotensin; Angiotensin II; Angiotensinogen; Apolipoprotein B; Apolipoproteins; Blood pressure; Cardiovascular diseases; Cholesterol; Density; Deoxyribonucleic acid; Diabetes; Diabetes mellitus (non-insulin dependent); DNA; EDTA; Ethnicity; Gene polymorphism; Genes; Genetic aspects; Genetic polymorphisms; Genomes; Glucose; Haplotypes; Homeostasis; Hypertension; Insulin; Insulin resistance; Laboratories; Lipase; Lipoprotein lipase; Lipoproteins; Low density lipoproteins; Medical research; Metabolic disorders; Metabolic syndrome; Musculoskeletal system; Obesity; Pathogenesis; Polymorphism; Population; Reverse transcription; Transcription (Genetics); Triglycerides; Type 2 diabetes; Variables; Womens health; Kazakhstan; China

Hyperinsulinism and insulin resistance are closely associated with several common diseases including type 2 of diabetes, cardiovascular diseases, and metabolic syndrome. The present study aimed to determine the association between hyperinsulinism, insulin resistance and the polymorphism of genes, in...