Ocular findings after bone marrow transplantation in a pediatric population
With the increasing use of bone marrow transplantation (BMT) in children to treat diseases of the hematopoietic system, ocular complications have been recognized in greater numbers. The authors performed a retrospective study to determine the prevalence and types of ocular abnormalities in a pediatr...
Saved in:
Published in | Ophthalmology (Rochester, Minn.) Vol. 106; no. 8; pp. 1564 - 1570 |
---|---|
Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
New York, NY
Elsevier Inc
01.08.1999
Elsevier |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | With the increasing use of bone marrow transplantation (BMT) in children to treat diseases of the hematopoietic system, ocular complications have been recognized in greater numbers. The authors performed a retrospective study to determine the prevalence and types of ocular abnormalities in a pediatric population following BMT.
Retrospective noncomparative study.
One hundred and four consecutive pediatric patients with aplastic anemia and various hematologic malignancies who required BMT.
Bone marrow transplantation.
Visual acuity and slit-lamp biomicroscopic and funduscopic examinations.
Ocular changes developed in 51% of patients. The most frequent findings included dry eye syndrome (12.5%), cataract (23.0%), and posterior segment complications (13.5%). A final visual acuity of 20/40 or better was achieved in 95.7% of eyes.
Pediatric patients can develop severe and potentially vision-threatening complications following BMT. Despite the high incidence of anterior and posterior segment abnormalities, ocular symptoms were generally mild and the majority of patients retained excellent visual function. Factors associated with ocular complications included the underlying disease, total body irradiation, systemic chemotherapy, graft-versus-host disease, and immunosuppression. Familiarity with these risk factors and potential complications in pediatric patients is important for successful treatment. |
---|---|
AbstractList | With the increasing use of bone marrow transplantation (BMT) in children to treat diseases of the hematopoietic system, ocular complications have been recognized in greater numbers. The authors performed a retrospective study to determine the prevalence and types of ocular abnormalities in a pediatric population following BMT.
Retrospective noncomparative study.
One hundred and four consecutive pediatric patients with aplastic anemia and various hematologic malignancies who required BMT.
Bone marrow transplantation.
Visual acuity and slit-lamp biomicroscopic and funduscopic examinations.
Ocular changes developed in 51% of patients. The most frequent findings included dry eye syndrome (12.5%), cataract (23.0%), and posterior segment complications (13.5%). A final visual acuity of 20/40 or better was achieved in 95.7% of eyes.
Pediatric patients can develop severe and potentially vision-threatening complications following BMT. Despite the high incidence of anterior and posterior segment abnormalities, ocular symptoms were generally mild and the majority of patients retained excellent visual function. Factors associated with ocular complications included the underlying disease, total body irradiation, systemic chemotherapy, graft-versus-host disease, and immunosuppression. Familiarity with these risk factors and potential complications in pediatric patients is important for successful treatment. PURPOSEWith the increasing use of bone marrow transplantation (BMT) in children to treat diseases of the hematopoietic system, ocular complications have been recognized in greater numbers. The authors performed a retrospective study to determine the prevalence and types of ocular abnormalities in a pediatric population following BMT.DESIGNRetrospective noncomparative study.PARTICIPANTSOne hundred and four consecutive pediatric patients with aplastic anemia and various hematologic malignancies who required BMT.INTERVENTIONBone marrow transplantation.MAIN OUTCOME MEASURESVisual acuity and slit-lamp biomicroscopic and funduscopic examinations.RESULTSOcular changes developed in 51% of patients. The most frequent findings included dry eye syndrome (12.5%), cataract (23.0%), and posterior segment complications (13.5%). A final visual acuity of 20/40 or better was achieved in 95.7% of eyes.CONCLUSIONSPediatric patients can develop severe and potentially vision-threatening complications following BMT. Despite the high incidence of anterior and posterior segment abnormalities, ocular symptoms were generally mild and the majority of patients retained excellent visual function. Factors associated with ocular complications included the underlying disease, total body irradiation, systemic chemotherapy, graft-versus-host disease, and immunosuppression. Familiarity with these risk factors and potential complications in pediatric patients is important for successful treatment. |
Author | Ruttum, Mark S Mieler, William F Suh, Donny W Stuckenschneider, Bradley J Kivlin, Jane D |
Author_xml | – sequence: 1 givenname: Donny W surname: Suh fullname: Suh, Donny W organization: The Eye Institute, Medical College of Wisconsin, Milwaukee, Wisconsin USA – sequence: 2 givenname: Mark S surname: Ruttum fullname: Ruttum, Mark S organization: The Eye Institute, Medical College of Wisconsin, Milwaukee, Wisconsin USA – sequence: 3 givenname: Bradley J surname: Stuckenschneider fullname: Stuckenschneider, Bradley J organization: The Eye Institute, Medical College of Wisconsin, Milwaukee, Wisconsin USA – sequence: 4 givenname: William F surname: Mieler fullname: Mieler, William F organization: The Eye Institute, Medical College of Wisconsin, Milwaukee, Wisconsin USA – sequence: 5 givenname: Jane D surname: Kivlin fullname: Kivlin, Jane D organization: The Eye Institute, Medical College of Wisconsin, Milwaukee, Wisconsin USA |
BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1907800$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/10442905$$D View this record in MEDLINE/PubMed |
BookMark | eNqFkDtPwzAQgC0Eghb4CSAPCMEQOLu2G08IIV4CiQGYLce5IKPUCXYK4t_j0grYWO6G--71jcl66AISssfghAFTp485sEIJDkdaH2sQUhR8jYyYFLoQUzZZJ6MfZIuMU3oFAKUmYpNsMRCCa5Ajcvfg5q2NtPGh9uElUdsMGGmVl9GZjbH7oEO0IfWtDYMdfBeoD9TSHmtvh-gd7bs-T1hUdshGY9uEu6u8TZ6vLp8ubor7h-vbi_P7wgmphkLzUpa1Rg5Oc6uh4aVyZWVL1Bwk0yWrmgodKmkrZBxlIzhO7VRa7ipwbrJNDpdz-9i9zTENZuaTwzafiN08GaW15EqoDMol6GKXUsTG9NHnrz4NA7OwaL4tmoUio7X5tmh47ttfLZhXM6z_dC21ZeBgBdjkbNtkQ86nX07DtATI2NkSw2zj3WM0yXkMLruL6AZTd_6fS74AIrKQ8w |
CODEN | OPHTDG |
CitedBy_id | crossref_primary_10_1097_00055735_200312000_00018 crossref_primary_10_3109_08880018_2012_725198 crossref_primary_10_1097_ICO_0000000000002659 crossref_primary_10_1097_01_icu_0000143684_22362_46 crossref_primary_10_1016_j_ajo_2020_01_025 crossref_primary_10_1097_ICO_0000000000000395 crossref_primary_10_1111_apa_13173 crossref_primary_10_1038_eye_2001_29 crossref_primary_10_1016_j_jaapos_2014_07_086 crossref_primary_10_1088_1742_6596_1947_1_012053 crossref_primary_10_1111_j_1755_3768_2007_01120_x crossref_primary_10_1111_j_1755_3768_2009_01634_x crossref_primary_10_1097_00055735_200012000_00002 crossref_primary_10_1016_j_ophtha_2009_04_054 crossref_primary_10_1007_s00417_015_2964_8 crossref_primary_10_1016_j_jfo_2008_11_001 crossref_primary_10_1016_S1542_0124_12_70082_4 crossref_primary_10_1016_S1542_0124_12_70104_0 crossref_primary_10_1016_j_jaapos_2005_06_002 crossref_primary_10_3389_fmed_2023_1133381 crossref_primary_10_1111_j_1600_0420_2007_00991_x crossref_primary_10_1007_s10384_004_0205_5 crossref_primary_10_1038_s41433_022_02250_9 crossref_primary_10_1097_ICU_0b013e328356230f crossref_primary_10_1016_j_jaapos_2017_10_010 crossref_primary_10_4103_IJO_IJO_2820_22 crossref_primary_10_1016_S0002_9394_00_00928_4 crossref_primary_10_1016_S1542_0124_12_70207_0 crossref_primary_10_1016_j_cnp_2017_02_001 crossref_primary_10_1097_ICL_0000000000001076 crossref_primary_10_1016_j_sjopt_2013_06_007 crossref_primary_10_1016_j_bbmt_2016_01_023 crossref_primary_10_1016_j_jtos_2021_08_013 crossref_primary_10_1111_j_1600_0420_2007_01120_x crossref_primary_10_1097_ICO_0b013e3181ea9a6b crossref_primary_10_1016_S0886_3350_01_01165_8 crossref_primary_10_1080_17469899_2019_1598860 |
ContentType | Journal Article |
Copyright | 1999 American Academy of Ophthalmology, Inc. 1999 INIST-CNRS |
Copyright_xml | – notice: 1999 American Academy of Ophthalmology, Inc. – notice: 1999 INIST-CNRS |
DBID | IQODW CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
DOI | 10.1016/S0161-6420(99)90454-2 |
DatabaseName | Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | MEDLINE MEDLINE - Academic |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine |
EISSN | 1549-4713 |
EndPage | 1570 |
ExternalDocumentID | 10_1016_S0161_6420_99_90454_2 10442905 1907800 S0161642099904542 |
Genre | Research Support, Non-U.S. Gov't Journal Article |
GroupedDBID | --- --K .1- .55 .FO .GJ 0R~ 123 1B1 1P~ 1~5 29N 4.4 457 4G. 53G 5RE 5VS 7-5 71M AAEDT AAEDW AAIAV AALRI AAQFI AAQQT AAQXK AAXUO ABCQX ABFRF ABJNI ABLJU ABMAC ABOCM ACGFO ACGFS ACIUM ACNCT ADMUD ADPAM AEFWE AENEX AEVXI AFFNX AFRHN AFTJW AGZHU AHPSJ AITUG AJUYK ALMA_UNASSIGNED_HOLDINGS ALXNB AMRAJ BELOY C5W CS3 DU5 EBS EFJIC EJD F5P FDB FEDTE FGOYB GBLVA HVGLF HZ~ IHE J1W K-O KOM L7B M27 M41 MO0 N4W N9A NQ- O9- OF- OPF OQ~ P2P R2- RIG ROL RPZ SDG SEL SES SSZ UHS UNMZH UV1 WH7 X7M XH2 XPP Z5R ZA5 ZGI ZXP 08R AAUGY ABPTK IQODW AFJKZ AKRWK CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
ID | FETCH-LOGICAL-c456t-92858d9e20c92a90f286c8ba8e92051981bfbece65abe12e5f42e7a75a2cb0cc3 |
ISSN | 0161-6420 |
IngestDate | Fri Aug 16 07:29:05 EDT 2024 Fri Aug 23 03:15:11 EDT 2024 Sat Sep 28 07:35:15 EDT 2024 Sun Oct 29 17:09:57 EDT 2023 Fri Feb 23 02:26:57 EST 2024 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 8 |
Keywords | Human Homograft Posterior segment Anterior segment Retrospective Eye Eye disease Treatment Surgery Bone marrow Graft Complication Child Anterior segment disease |
Language | English |
License | CC BY 4.0 |
LinkModel | OpenURL |
MergedId | FETCHMERGED-LOGICAL-c456t-92858d9e20c92a90f286c8ba8e92051981bfbece65abe12e5f42e7a75a2cb0cc3 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
PMID | 10442905 |
PQID | 69952646 |
PQPubID | 23479 |
PageCount | 7 |
ParticipantIDs | proquest_miscellaneous_69952646 crossref_primary_10_1016_S0161_6420_99_90454_2 pubmed_primary_10442905 pascalfrancis_primary_1907800 elsevier_sciencedirect_doi_10_1016_S0161_6420_99_90454_2 |
PublicationCentury | 1900 |
PublicationDate | 1999-08-01 |
PublicationDateYYYYMMDD | 1999-08-01 |
PublicationDate_xml | – month: 08 year: 1999 text: 1999-08-01 day: 01 |
PublicationDecade | 1990 |
PublicationPlace | New York, NY |
PublicationPlace_xml | – name: New York, NY – name: United States |
PublicationTitle | Ophthalmology (Rochester, Minn.) |
PublicationTitleAlternate | Ophthalmology |
PublicationYear | 1999 |
Publisher | Elsevier Inc Elsevier |
Publisher_xml | – name: Elsevier Inc – name: Elsevier |
References | Robertson (BIB1) 1996 Coskuncan, Jabs, Dunn (BIB14) 1994; 112 Jack, Hicks (BIB13) 1981; 13 Franklin, Kenyon, Tutschka (BIB7) 1983; 90 Deeg, Flournoy, Sullivan (BIB20) 1984; 10 Bray, Carey, Proctor (BIB19) 1991; 75 Ng, Lam, Li (BIB23) 1999; 106 Bernauer, Gratwohl (BIB29) 1992; 113 Jabs, Hirst, Green (BIB6) 1983; 101 Cunningham, Irvine, Rugo (BIB15) 1996; 122 Brown, Shields, Sanborn (BIB28) 1982; 89 Lopez, Sternberg, Dabbs (BIB26) 1991; 112 Belkacemi, Ozsahin, Pene (BIB16) 1996; 35 De Marco, Dassio, Vittone (BIB18) 1996; 6 Jabs, Wingard, Green (BIB2) 1989; 107 Mathé, Amiel, Schwarzenberg (BIB11) 1965; 25 Calissendorff, Bolme (BIB17) 1993; 77 Ohkoshi, Tsiaras (BIB30) 1992; 76 Perrers-Taylor, Brinkley, Reynolds (BIB27) 1965; 3 Wingard, Piantadosi, Santos (BIB8) 1990; 8 Parsons, Fitzgerald, Hood (BIB24) 1983; 9 Thomas, Storb, Clift (BIB3) 1975; 292 Elfenbein, Mellits, Santos (BIB9) 1983; 15 Slavin, Santos (BIB4) 1973; 1 Livesey, Holmes, Whittaker (BIB22) 1989; 3 Gloor, Gratwohl, Hahn (BIB25) 1985; 69 Hoover, Smith, Turner (BIB21) 1988; 95 Hirst, Jabs, Tutschka (BIB5) 1983; 101 Dunn, Jabs, Wingard (BIB10) 1993; 111 Thomas (BIB12) 1995; 38 |
References_xml | – volume: 112 start-page: 372 year: 1994 end-page: 379 ident: BIB14 article-title: The eye in bone marrow transplantation. VI. Retinal complications publication-title: Arch Ophthalmol contributor: fullname: Dunn – volume: 111 start-page: 1367 year: 1993 end-page: 1373 ident: BIB10 article-title: Bone marrow transplantation and cataract development publication-title: Arch Ophthalmol contributor: fullname: Wingard – volume: 1 start-page: 472 year: 1973 end-page: 498 ident: BIB4 article-title: The graft versus host reaction in man after bone marrow transplantation publication-title: Clin Immunol Immunopathol contributor: fullname: Santos – volume: 90 start-page: 4 year: 1983 end-page: 13 ident: BIB7 article-title: Ocular manifestations of graft-vs-host disease publication-title: Ophthalmology contributor: fullname: Tutschka – volume: 3 start-page: 431 year: 1965 ident: BIB27 article-title: Choroido-retinal damage as a complication of radiotherapy publication-title: Acta Radiol contributor: fullname: Reynolds – volume: 15 start-page: 1412 year: 1983 end-page: 1416 ident: BIB9 article-title: Patients with aplastic anemia publication-title: Transplant Proc contributor: fullname: Santos – volume: 113 start-page: 604 year: 1992 end-page: 605 ident: BIB29 article-title: Bone marrow transplant retinopathy publication-title: Am J Ophthalmol contributor: fullname: Gratwohl – volume: 69 start-page: 320 year: 1985 end-page: 325 ident: BIB25 article-title: Multiple cotton wool spots following bone marrow transplantation for treatment of acute lymphatic leukaemia publication-title: Br J Ophthalmol contributor: fullname: Hahn – volume: 101 start-page: 585 year: 1983 end-page: 590 ident: BIB6 article-title: The eye in bone marrow transplantation. II. Histopathology publication-title: Arch Ophthalmol contributor: fullname: Green – volume: 13 start-page: 709 year: 1981 end-page: 711 ident: BIB13 article-title: Ocular complications in high-dose chemoradiotherapy and marrow transplantation publication-title: Ann Ophthalmol contributor: fullname: Hicks – volume: 106 start-page: 160 year: 1999 end-page: 164 ident: BIB23 article-title: Ocular complications of pediatric bone marrow transplantation publication-title: Ophthalmology contributor: fullname: Li – volume: 38 start-page: 230 year: 1995 end-page: 237 ident: BIB12 article-title: History, current results, and research in marrow transplantation publication-title: Perspect Biol Med contributor: fullname: Thomas – volume: 75 start-page: 611 year: 1991 end-page: 614 ident: BIB19 article-title: Ocular complications of bone marrow transplantation publication-title: Br J Ophthalmol contributor: fullname: Proctor – volume: 122 start-page: 268 year: 1996 end-page: 270 ident: BIB15 article-title: Bone marrow transplantation retinopathy in the absence of radiation therapy publication-title: Am J Ophthalmol contributor: fullname: Rugo – volume: 6 start-page: 436 year: 1996 end-page: 439 ident: BIB18 article-title: A retrospective study of ocular side effects in children undergoing bone marrow transplantation publication-title: Eur J Ophthalmol contributor: fullname: Vittone – volume: 107 start-page: 1343 year: 1989 end-page: 1348 ident: BIB2 article-title: The eye in bone marrow transplantation. III. Conjunctival graft-vs-host disease publication-title: Arch Ophthalmol contributor: fullname: Green – volume: 8 start-page: 820 year: 1990 end-page: 830 ident: BIB8 article-title: Allogeneic bone marrow transplantation for patients with high-risk acute lymphoblastic leukemia publication-title: J Clin Oncol contributor: fullname: Santos – volume: 10 start-page: 957 year: 1984 end-page: 964 ident: BIB20 article-title: Cataracts after total body irradiation and marrow transplantation publication-title: Int J Radiat Oncol Biol Phys contributor: fullname: Sullivan – start-page: 599 year: 1996 end-page: 609 ident: BIB1 article-title: Bone Marrow transplantation publication-title: Nelson Textbook of Pediatrics contributor: fullname: Robertson – volume: 3 start-page: 271 year: 1989 end-page: 276 ident: BIB22 article-title: Ocular complications of bone marrow transplantation publication-title: Eye contributor: fullname: Whittaker – volume: 95 start-page: 151 year: 1988 end-page: 155 ident: BIB21 article-title: Ophthalmic evaluation of survivors of acute lymphoblastic leukemia publication-title: Ophthalmology contributor: fullname: Turner – volume: 89 start-page: 1494 year: 1982 end-page: 1501 ident: BIB28 article-title: Radiation retinopathy publication-title: Ophthalmology contributor: fullname: Sanborn – volume: 35 start-page: 53 year: 1996 end-page: 60 ident: BIB16 article-title: Cataractogenesis after total body irradiation publication-title: Int J Radiat Oncol Biol Phys contributor: fullname: Pene – volume: 25 start-page: 179 year: 1965 end-page: 195 ident: BIB11 article-title: Successful allogenic bone marrow transplantation in man publication-title: Blood contributor: fullname: Schwarzenberg – volume: 77 start-page: 36 year: 1993 end-page: 38 ident: BIB17 article-title: Cataract development and outcome of surgery in bone marrow transplanted children publication-title: Br J Ophthalmol contributor: fullname: Bolme – volume: 112 start-page: 635 year: 1991 end-page: 646 ident: BIB26 article-title: Bone marrow transplant retinopathy publication-title: Am J Ophthalmol contributor: fullname: Dabbs – volume: 101 start-page: 580 year: 1983 end-page: 584 ident: BIB5 article-title: The eye in bone marrow transplantation. I. Clinical study publication-title: Arch Ophthalmol contributor: fullname: Tutschka – volume: 292 start-page: 832 year: 1975 end-page: 843 ident: BIB3 article-title: Bone-marrow transplantation (first of two parts) publication-title: N Engl J Med contributor: fullname: Clift – volume: 9 start-page: 609 year: 1983 end-page: 622 ident: BIB24 article-title: The effects of irradiation on the eye and optic nerve publication-title: Int J Radiat Oncol Biol Phys contributor: fullname: Hood – volume: 76 start-page: 651 year: 1992 end-page: 655 ident: BIB30 article-title: Prognostic importance of ophthalmic manifestations in childhood leukaemia publication-title: Br J Ophthalmol contributor: fullname: Tsiaras |
SSID | ssj0006634 |
Score | 1.8239491 |
Snippet | With the increasing use of bone marrow transplantation (BMT) in children to treat diseases of the hematopoietic system, ocular complications have been... PURPOSEWith the increasing use of bone marrow transplantation (BMT) in children to treat diseases of the hematopoietic system, ocular complications have been... |
SourceID | proquest crossref pubmed pascalfrancis elsevier |
SourceType | Aggregation Database Index Database Publisher |
StartPage | 1564 |
SubjectTerms | Adolescent Adult Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Bone Marrow Transplantation - adverse effects Bone marrow, stem cells transplantation. Graft versus host reaction Child Child, Preschool Eye Diseases - diagnosis Eye Diseases - etiology Female Fluorescein Angiography Hematologic Diseases - therapy Humans Infant Leukemia - therapy Male Medical sciences Prevalence Retrospective Studies Risk Factors Transfusions. Complications. Transfusion reactions. Cell and gene therapy Visual Acuity |
Title | Ocular findings after bone marrow transplantation in a pediatric population |
URI | https://dx.doi.org/10.1016/S0161-6420(99)90454-2 https://www.ncbi.nlm.nih.gov/pubmed/10442905 https://search.proquest.com/docview/69952646 |
Volume | 106 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1ba9swFBZbCmMwxu7Ltm56WGEjOJMVy5Eey9ZSlqaBJqF5E7It00KrmsZ52a_fkSVfsq1024sxAktG55P0naNzQeijyhhRI2BuNEtJEHGiggSOgYDzPIu0CBVJrEF_ehIfLaPvK7Zqndir6JIyGaY__hhX8j9ShTaQq42S_QfJNp1CA7yDfOEJEobnX8l45pxIq3tnW33TFfxOro31SrXJFW0FCLMuLpXxToUXZqAGRV2eY1A05bu6JHVWnJfn6vLKpWeqbAy-rJZztDdm2DEgzDeVZebboLHWnG7K0pVPnraW1XlpPTgMKNPGptZyRoL2UmpqA92rxjPvbJz52DzROMI11kmQMig0ZGt7JXEHR7yzWdo8NZ2DN2SuhMhvm7qzL8yb3veskrhnz9GIRT54ciuR9slMHi6Pj-XiYLW4j3boWDDWQzv7k9OzSXNMA9Xyid9dr21415d2qE9CfPbD3EZcHhVqDcspd3VQbldUKsKyeIIee00D7zvYPEX3tHmGHky9L8VzNHHowTV6cIUebNGDHXrwL-jBFwYr3KAHt-h5gZaHB4uvR4EvrRGkwJjLQFDOeCY0JamgSpCc8jjlieJaUEvqQZnJYXXrmKlEh1SzPKJ6rMZM0TQhaTp6iXoG_uc1womOWBqP4ijJbbkCocYitdffochA-9VRHw3reZOFy6AiO66FcSjtREshZDXRkvYRr2dXehro6J0EQNz16e6WNNoBBVBhQvroQy0dCduovRtTRl9v1jIWgoFuEPfRKye0zr9GwNkIe3Pnt2_Rw3ZVvEO98majd4Gylsl7D76fWi-R7A |
link.rule.ids | 315,786,790,27955,27956 |
linkProvider | Library Specific Holdings |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Ocular+findings+after+bone+marrow+transplantation+in+a+pediatric+population&rft.jtitle=Ophthalmology+%28Rochester%2C+Minn.%29&rft.au=Suh%2C+D+W&rft.au=Ruttum%2C+M+S&rft.au=Stuckenschneider%2C+B+J&rft.au=Mieler%2C+W+F&rft.date=1999-08-01&rft.issn=0161-6420&rft.volume=106&rft.issue=8&rft.spage=1564&rft.epage=1570&rft_id=info:doi/10.1016%2FS0161-6420%2899%2990454-2&rft.externalDBID=NO_FULL_TEXT |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0161-6420&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0161-6420&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0161-6420&client=summon |