Elevated baseline circulating platelet-to-lymphocyte ratio and survival in initial stage Ⅳ gastric cancer patients: A meta-analysis

• Published in: PloS one Vol. 17; no. 4; p. e0265897
• Main Authors: Hu, Guoming, Wang, Shimin, Wang, Songxiang, Huang, Liming
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.01.2022; Public Library of Science (PLoS)
• Subjects: Biology and Life Sciences; Biomarkers; Blood platelets; Blood Platelets - pathology; Cancer; Cell survival; Chemotherapy; Clinical outcomes; Gastric cancer; Humans; Inflammation; Inflammatory response; Lymphocytes; Lymphocytes - pathology; Medical prognosis; Medicine; Medicine and Health Sciences; Meta-analysis; Metastases; Metastasis; Neutrophils - pathology; Patients; Physical Sciences; Platelets; Prognosis; Research and Analysis Methods; Sensitivity analysis; Stomach cancer; Stomach Neoplasms - pathology; Survival; Thyroid gland; Thyroidectomy; Tumors; China

Systemic inflammatory response (SIR) plays important roles in initiation, promotion and progression of tumor. However, the prognostic role of baseline circulating platelet-to-lymphocyte ratio (PLR) (known as a marker of SIR) in human initial stage Ⅳ gastric cancer (GC) remains controversial. Hence,...