The protection of bisphenol A-modulated miRNAs and targets by natural products

• Published in: Environment international Vol. 196; p. 109299
• Main Authors: Chuang, Ya-Ting, Yen, Ching-Yu, Liu, Wangta, Chien, Tsu-Ming, Chang, Fang-Rong, Tsai, Yi-Hong, Tang, Jen-Yang, Chang, Hsueh-Wei
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.02.2025; Elsevier
• Subjects: antioxidants; Benzhydryl Compounds - toxicity; bioinformatics; Biological Products - pharmacology; Bisphenol A; Bisphenol A Compounds; Endocrine Disruptors - toxicity; environment; Environmental Pollutants - toxicity; health services; Humans; microRNA; MicroRNAs - metabolism; miRNAs; Natural products; Oxidative stress; Phenols - toxicity; pollutants; protein-protein interactions; STRING; Targets; toxicity; Bisphenol A; Oxidative stress; STRING; Targets; miRNAs; Natural products

[Display omitted] •Humans face the inevitable exposure of endocrine-disrupting bisphenol A (BPA).•Targets/miRNAs are controlled by BPA but lack a protective link to natural products.•This review classifies BPA-down-/up-regulated targets in the network.•Natural products are innovatively integrated in...