Assessment of attention threshold in rats by titration of visual cue duration during the five choice serial reaction time task

• Published in: Journal of neuroscience methods Vol. 241; pp. 37 - 43
• Main Authors: Martin, Thomas J., Grigg, Amanda, Kim, Susy A., Ririe, Douglas G., Eisenach, James C.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 15.02.2015
• Subjects: Animals; Attention; Attention - physiology; Behavior; Choice Behavior - physiology; Cues; Impulsivity; Male; Photic Stimulation - methods; Psychomotor Performance - physiology; Rats; Rats, Inbred F344; Reaction Time - physiology; Reinforcement; Threshold; Time Factors; Impulsivity; Attention; Reinforcement; 5CSRTT; Behavior; ITI; MCD; Threshold

•We report a novel variant of the 5CSRTT that systematically titrates the level of task difficulty.•This variant of the 5CSRTT reduces the training period significantly compared to other methods.•The median cue duration is sensitive to manipulations known to alter attention performance.•This method...