Topical transport of hydrophilic compounds using water-in-oil nanoemulsions - Wu, Huailiang; Ramachandran, Chandrasekharan; Weiner, Norman D; Roessler, Blake J (International journal of pharmaceutics, 2001)
Keywords: Administration, Topical; Animals; Biological and medical sciences; Biological Transport - drug effects; Chemistry, Pharmaceutical; Emulsions - pharmacology; General pharmacology; HLB; Hydrophilic drug; Inulin - administration & dosage; Inulin - pharmacokinetics; Linear Models; Male; Medical sciences; Mice; Mice, Inbred ICR; Nanoemulsions; Pharmaceutical technology. Pharmaceutical industry; Pharmacology. Drug treatments; Rats; Rats, Sprague-Dawley; Sebum; Skin Absorption - drug effects; Skin transport; Species Specificity; Transfollicular; Skin transport; Nanoemulsions; Hydrophilic drug; Sebum; Transfollicular; HLB; Water oil emulsion; Rat; Biological transport; Drug carrier; Strain specificity; Surfactant; Molecular weight; Ethylene oxide polymer; Hydrophilic lipophilic balance; Formulation; Inulin; Hydrophilic compound; Diffusion; Pharmaceutical technology; Non ionic surfactant; Rodentia; Permeation; Olive oil; In vitro; Vertebrata; Mammalia; Mouse; Animal; Dosage form; Sorbitan oleate; Skin; Physicochemical properties; Topical administration