Association of SHBG gene polymorphism with menarche

• Published in: Molecular human reproduction Vol. 11; no. 6; pp. 459 - 462
• Main Authors: Xita, N., Tsatsoulis, A., Stavrou, I., Georgiou, I.
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.06.2005; Oxford Publishing Limited (England)
• Subjects: Adolescent; Alleles; Biological and medical sciences; Embryology: invertebrates and vertebrates. Teratology; Female; Fundamental and applied biological sciences. Psychology; gene; Greece; Humans; menarche; Menarche - genetics; Minisatellite Repeats; Polymorphism, Genetic; polymorphisms; Receptors, Cell Surface - genetics; SHBG; Greece; Human; Menarche; Polymorphism; gene/menarche/polymorphisms/SHBG

The age of menarche may be subject to hereditary influences but the specific determinants are unknown. Our aim was to investigate the possible association of a functional (TAAAA)n polymorphism in the promoter of the sex hormone-binding globulin (SHBG) gene with the timing of menarche. This polymorph...