A multicenter comparison of isoflurane and propofol as adjuncts to remifentanil-based anesthesia

• Published in: Journal of clinical anesthesia Vol. 12; no. 2; pp. 129 - 135
• Main Authors: Wilhelm, Wolfram, Grundmann, Ulrich, Van Aken, Hugo, Haus, Eva-Maria, Larsen, Reinhard
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.03.2000; Elsevier Science
• Subjects: Adult; Analgesic; Anesthesia Recovery Period; Anesthesia, Intravenous; anesthetic; Anesthetics, Inhalation - administration & dosage; Anesthetics, Intravenous - administration & dosage; Anesthetics, Intravenous - adverse effects; Anesthetics. Neuromuscular blocking agents; Awareness - drug effects; Biological and medical sciences; Blood Pressure - drug effects; Elective Surgical Procedures; Female; Heart Rate - drug effects; hemodynamics; Humans; inhalational; intravenous; Intubation, Intratracheal; isoflurane; Isoflurane - administration & dosage; Male; Medical sciences; Neuropharmacology; opioid; Pharmacology. Drug treatments; Piperidines - administration & dosage; Piperidines - adverse effects; Postoperative Nausea and Vomiting - etiology; propofol; Propofol - administration & dosage; Prospective Studies; recovery; remifentanil; Respiration - drug effects; Shivering - drug effects; side effects; Time Factors; anesthetic; Analgesic; intravenous; propofol; opioid; side effects; remifentanil; recovery; inhalational; isoflurane; hemodynamics; Volatile compound; Human; Toxicity; General anesthesia; Opiates; Narcotic analgesic; Recovery; Isoflurane; Remifentanil; General anesthetic; Awakening; Hemodynamics; Propofol; Technique; Comparative study; Halogen Organic compounds

Study Objective: To compare recovery, hemodynamics, and side effects of remifentanil-based anesthesia with hypnotic concentrations of isoflurane or propofol. Design: Multicenter, prospective, randomized, two-group study. Setting: 15 university and 5 municipal hospitals. Patients: 249 ASA physical st...