Characterization of hemoglobin, water, and NIR scattering in breast tissue: analysis of intersubject variability and menstrual cycle changes

• Published in: Journal of biomedical optics Vol. 9; no. 3; p. 541
• Main Authors: Pogue, Brian W, Jiang, Shudong, Dehghani, Hamid, Kogel, Christine, Soho, Sandra, Srinivasan, Subhadra, Song, Xiaomei, Tosteson, Tor D, Poplack, Steven P, Paulsen, Keith D
• Format: Journal Article
• Language: English
• Published: United States 01.05.2004
• Subjects: Adult; Breast - metabolism; Female; Hemoglobins - metabolism; Humans; Image Interpretation, Computer-Assisted - methods; Menstrual Cycle - physiology; Middle Aged; Postmenopause - physiology; Premenopause - physiology; Reference Values; Reproducibility of Results; Scattering, Radiation; Sensitivity and Specificity; Spectrophotometry, Infrared - instrumentation; Spectrophotometry, Infrared - methods; Tomography, Optical - instrumentation; Tomography, Optical - methods; Water - physiology

Near-infrared imaging was used to quantify typical values of hemoglobin concentration, oxygen saturation, water fraction, scattering power, and scattering amplitude within the breast tissue of volunteer subjects. A systematic study of the menstrual variations in these parameters was carried out by m...