High Expression of MORC2 is Associated with Poor Clinical Outcomes and Immune Infiltrates in Colon Adenocarcinoma

• Published in: International journal of general medicine Vol. 16; pp. 4595 - 4615
• Main Authors: Zhao, Peizhuang, Ning, Jiajia, Huang, Jun, Wei, Binqian, Wang, Zhen, Huang, Xue
• Format: Journal Article
• Language: English
• Published: Dove Medical Press Limited 31.10.2023; Dove; Dove Medical Press
• Subjects: Adenocarcinoma; B cells; biomarker; Cancer; Cancer patients; Chromatin; colon adenocarcinoma; Colon cancer; Development and progression; diagnosis; Gene expression; Genes; Genetic aspects; Genomes; Genomics; immune cell infiltration; Immunotherapy; Killer cells; morc2; Original Research; Patient outcomes; Prognosis

Purpose: Microrchidia 2 (MORC2) is a universally expressed molecule that has recently been identified as a chromatin modulator and elevated in many malignancies. However, its prognostic value and immunological role of MORC2 in colon adenocarcinoma (COAD) have never been illustrated. Methods: The cli...