Pharmacokinetics and Pharmacodynamics of a Fixed-Dose Combination of Esomeprazole and Magnesium Hydroxide Compared to the Enteric-Coated Esomeprazole - Kim, Yoonjin; Bae, Sungyeun; Jeon, Inseung; Kwon, Jihoon; Hong, Sung Hee; Kim, Na Young; Yu, Kyung-Sang; Jang, In-Jin; Lee, SeungHwan (Clinical therapeutics, 2024)
Keywords: Acidity; Acids; Adult; Adults; Antacids; Antacids - administration & dosage; Antacids - pharmacology; Catheters; Coatings; Comparative pharmacokinetics/pharmacodynamics; Cross-Over Studies; Drug Combinations; Drug development; Drug dosages; Esomeprazole - administration & dosage; Esomeprazole - pharmacokinetics; Esomeprazole - pharmacology; Esophagus; Female; Gastric juice; Gastroesophageal reflux; Gastroesophageal reflux disease; Healthy Volunteers; Humans; Immediate release; Internal Medicine; Magnesium; Magnesium Hydroxide - administration & dosage; Male; Middle Aged; Omeprazole; Pharmacodynamics; Pharmacokinetics; Proton pump inhibitors; Proton Pump Inhibitors - administration & dosage; Proton Pump Inhibitors - pharmacokinetics; Proton Pump Inhibitors - pharmacology; Tablets, Enteric-Coated; Young Adult; Comparative pharmacokinetics/pharmacodynamics; Immediate release; GERD; TEAE; FDC; Gastroesophageal reflux disease; PPI; BMI; body mass index; treatment-emergent adverse event; fixed-dose combination; proton pump inhibitor