Long COVID-19 autoantibodies and their potential effect on fertility

• Published in: Frontiers in immunology Vol. 16; p. 1540341
• Main Authors: Talamini, Laura, Fonseca, Dennyson Leandro M., Kanduc, Darja, Chaloin, Olivier, Verdot, Cindy, Galmiche, Christian, Dotan, Arad, Filgueiras, Igor Salerno, Borghi, Maria Orietta, Meroni, Pier Luigi, Gavrilova, Natalia Y., Ryabkova, Varvara A., Churilov, Leonid P., Halpert, Gilad, Lensch, Christian, Thurner, Lorenz, Fong, Siew-Wai, Ng, Lisa F.P., Rénia, Laurent, Young, Barnaby E., Lye, David Chien, Lozano, José Manuel, Cabral-Marques, Otávio, Shoenfeld, Yehuda, Muller, Sylviane
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers 27.05.2025; Frontiers Media S.A
• Subjects: Adult; Animals; Antibodies, Viral - blood; Antibodies, Viral - immunology; autoantibodies; Autoantibodies - blood; Autoantibodies - immunology; coronavirus infection; COVID-19 - complications; COVID-19 - immunology; Cross Reactions; Female; Fertility - immunology; Humans; Immunology; Infertility, Male - immunology; Life Sciences; Male; male reproductive system; Mice; Middle Aged; peptide sequence identity; post-COVID-19 condition; Reproductive Biology; SARS-CoV-2 - immunology; Spike Glycoprotein, Coronavirus - immunology; coronavirus infection; peptide sequence identity; autoantibodies; post-COVID-19 condition; male reproductive system; autoantibodies peptide sequence identity male reproductive system coronavirus infection post-COVID-19 condition

Impaired spermatogenesis has been reported in coronavirus disease 2019 (COVID-19) patients. However, the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on male fertility remains unclear. The purpose of this multicenter study was to investigate the possible impact of SARS-CoV-...