Hypothyroidism impairs the host immune response during the acute phase of Chagas disease

• Published in: Immunobiology (1979) Vol. 225; no. 6; p. 152024
• Main Authors: Sampaio, Pedro Alexandre, Goulart, Amanda, Brazão, Vânia, Anchieta, Naira Ferreira, Providello, Maiara Voltarelli, Portapilla, Gisele Bulhões, Duarte, Andressa, da Silva, Jefferson Luiz, do Prado Júnior, José Clóvis
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier GmbH 01.11.2020
• Subjects: Hypothyroidism; Immunity; T. cruzi; Hypothyroidism; Immunity; T. cruzi

[Display omitted] •We have investigated the influence of hypothyroidism in the course of acute Trypanosoma cruzi infection.•Infected rats have higher IFN-γ and IL-17A levels compared with non-infected controls.•B cells and the ability of antigenic presentation of macrophages are negatively correlate...