Improved squalene production through increasing lipid contents in Saccharomyces cerevisiae - Wei, Liu‐Jing; Kwak, Suryang; Liu, Jing‐Jing; Lane, Stephan; Hua, Qiang; Kweon, Dae‐Hyuk; Jin, Yong‐Su (Biotechnology and bioengineering, 2018)
Keywords: ABC transporter; Accumulation; Acyl-CoA Oxidase - genetics; Acyl-CoA Oxidase - metabolism; ATP-Binding Cassette Transporters - genetics; ATP-Binding Cassette Transporters - metabolism; Baking yeast; Biofuels; Biosynthesis; diacylglycerol acyltransferase; Diacylglycerol O-Acyltransferase - genetics; Diacylglycerol O-Acyltransferase - metabolism; Diglycerides; Fermentation; Flavors; Gene Expression; HMG‐CoA reductase; Hydrophobicity; Hydroxymethylglutaryl CoA Reductases - genetics; Hydroxymethylglutaryl CoA Reductases - metabolism; lipid bodies; Lipid Metabolism; Lipids; Metabolic Engineering - methods; Metabolic Networks and Pathways - genetics; Mevalonic acid; Microorganisms; Molecular chains; Mutant Proteins - genetics; Mutant Proteins - metabolism; Oxidation; Pharmacology; Plant extracts; Plant tissues; Reductase; Saccharomyces cerevisiae; Saccharomyces cerevisiae - enzymology; Saccharomyces cerevisiae - genetics; Saccharomyces cerevisiae - growth & development; Saccharomyces cerevisiae - metabolism; Saccharomyces cerevisiae Proteins - genetics; Saccharomyces cerevisiae Proteins - metabolism; Squalene; Squalene - metabolism; Storage capacity; Yeast; β‐oxidation; β-oxidation; diacylglycerol acyltransferase; HMG-CoA reductase; Saccharomyces cerevisiae; squalene; lipid bodies