Successful combination therapy with corticosteroids, biweekly intravenous pulse cyclophosphamide and cyclosporin A for acute interstitial pneumonia in patients with dermatomyositis : report of three cases

• Published in: Japanese Journal of Clinical Immunology Vol. 36; no. 2; pp. 122 - 128
• Main Authors: SUZUKI, Akitake, SHOJI, Norikazu, KIKUCHI, Eigo, UEKUBO, Kazuaki, AOKI, Naoko, SONODA, Yui, TORIGAI, Hideyuki, YAMASHITA, Hiroyuki, FUJITA, Kentaro, OKAI, Takahiro
• Format: Journal Article
• Language: English
• Published: Japan The Japan Society for Clinical Immunology 2013
• Subjects: Acute Disease; Acute Interstitial Pneumonia; Adrenal Cortex Hormones - administration & dosage; Aged; Biweekly Intravenous pulse cyclophosphamide; Cyclophosphamide - administration & dosage; Cyclosporine - administration & dosage; Cyclosporine A; Dermatomyositis; Dermatomyositis - complications; Diffuse alveolar damage; Drug Therapy, Combination; Female; Humans; Lung Diseases, Interstitial - drug therapy; Male; Middle Aged; Pulse Therapy, Drug

We report three patients with dermatomyositis (DM) complicated with acute interstitial pneumonia (AIP). All of them complained of fever and acutely worsening dyspnea and were treated immediately by combination therapies with pulse therapy with methylprednisone (mPSL) followed by corticosteroids, biw...