Estimates of glomerular filtration rate from MR renography and tracer kinetic models

• Published in: Journal of magnetic resonance imaging Vol. 29; no. 2; pp. 371 - 382
• Main Authors: Bokacheva, Louisa, Rusinek, Henry, Zhang, Jeff L., Chen, Qun, Lee, Vivian S.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.02.2009
• Subjects: Adult; Aged; Aged, 80 and over; compartmental modeling; Contrast Media - pharmacokinetics; Female; gadolinium chelates; Gadolinium DTPA - pharmacokinetics; Glomerular Filtration Rate; Humans; Linear Models; Magnetic Resonance Imaging - methods; Male; Middle Aged; Monte Carlo Method; MR renography; Radioisotope Renography; renal function; Sensitivity and Specificity; Statistics, Nonparametric; tracer kinetics

Purpose To compare six methods for calculating the single‐kidney glomerular filtration rate (GFR) from T1‐weighted magnetic resonance (MR) renography (MRR) against reference radionuclide measurements. Materials and Methods In 10 patients, GFR was determined using six published methods: the Baumann–R...