Dynamic conformational changes of extracellular S5–P linkers in the hERG channel
The hERG channel has an unusually long ‘S5–P linker’ (residues 571–613) that lines the outer mouth of the pore. Previously, we have shown that residues along this S5–P linker are critical for the fast‐inactivation process and K+ selectivity of the hERG channel. Here we used several approaches to pro...
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Published in | The Journal of physiology Vol. 569; no. 1; pp. 75 - 89 |
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Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
9600 Garsington Road , Oxford , OX4 2DQ , UK
Blackwell Science Ltd
15.11.2005
Blackwell Science Inc |
Subjects | |
Online Access | Get full text |
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