Molecular characterization of enrofloxacin resistant Actinobacillus pleuropneumoniae isolates

• Published in: Veterinary microbiology Vol. 142; no. 3-4; pp. 309 - 312
• Main Authors: Wang, Yu-Chih, Chan, Jacky Peng-Wen, Yeh, Kuang-Sheng, Chang, Chao-Chin, Hsuan, Shih-Ling, Hsieh, Yi-Mei, Chang, Yi-Chih, Lai, Tan-Chen, Lin, Wen-Hsin, Chen, Ter-Hsin
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 19.05.2010; Elsevier
• Subjects: Actinobacillus pleuropneumoniae; Actinobacillus pleuropneumoniae - drug effects; Actinobacillus pleuropneumoniae - genetics; Actinobacillus pleuropneumoniae - isolation & purification; amino acid sequences; analogs & derivatives; animal pathogenic bacteria; Anti-Bacterial Agents; Anti-Bacterial Agents - pharmacology; antibiotic resistance; Arginine; Arginine - analogs & derivatives; Arginine - pharmacology; Bacteriology; Biological and medical sciences; Cephalosporins; Cephalosporins - pharmacology; codons; DNA Gyrase; DNA Gyrase - genetics; DNA topoisomerase (ATP-hydrolysing); DNA Topoisomerase IV; DNA Topoisomerase IV - genetics; drug effects; Drug Resistance, Bacterial; Drug Resistance, Bacterial - drug effects; Drug Resistance, Bacterial - genetics; Efflux pump; enrofloxacin; Enrofloxacin resistance; Fluoroquinolones; Fluoroquinolones - pharmacology; Fundamental and applied biological sciences. Psychology; Genes, Bacterial; Genes, Bacterial - genetics; genetics; hosts; isolation & purification; microbial genetics; Microbial Sensitivity Tests; Microbiology; minimum inhibitory concentration; Miscellaneous; Molecular Sequence Data; mutants; Mutation; Mutation - genetics; pharmacology; proton pump; Quinolone resistance-determining region; Serotyping; strain differences; swine; Taiwan; Thiamphenicol; Thiamphenicol - analogs & derivatives; Thiamphenicol - pharmacology; Taiwan; Enrofloxacin resistance; Quinolone resistance-determining region; Actinobacillus pleuropneumoniae; Efflux pump; Enrofloxacin; Pasteurellaceae; Resistance; Fluoroquinolone derivatives; Bacteria; Isolate; Antibacterial agent; Veterinary; Quinolone derivatives

Enrofloxacin (ER) resistant Actinobacillus pleuropneumoniae strains emerged in Taiwan in 2002. The mechanism of ER resistance in A. pleuropneumoniae has not yet been reported. A total of 48 A. pleuropneumoniae isolates were obtained from the lungs of pigs with pleuropneumonia in Taiwan between Septe...