Lipid–Polymer Hybrids Encapsulating Iron-Oxide Nanoparticles as a Label for Lateral Flow Immunoassays

• Published in: Biosensors (Basel) Vol. 11; no. 7; p. 218
• Main Authors: Bazsefidpar, Shayesteh, Moyano, Amanda, Gutiérrez, Gemma, Matos, María, Blanco-López, María Carmen
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.07.2021; MDPI
• Subjects: Biotin; Carbodiimide; COVID-19; Encapsulation; Ethanol; Hybrids; Immunoassay; Immunoassays; Iron oxides; Labels; lateral flow immunoassays (LFIA); lipid; Lipids; lipid–polymer hybrid nanoparticles; Microemulsions; Nanoparticles; PLGA; Polymers; Polyvinyl alcohol; Solvents; SPIONs; Surfactants; United States > US; Germany; Spain

The feasibility of using Superparamagnetic Iron Oxide Nanoparticles (SPIONs) encapsulated by lipid–polymer nanoparticles as labels in lateral flow immunoassays (LFIA) was studied. First, nanoparticles were synthesized with average diameters between 4 and 7 (nm) through precipitation in W/O microemul...