Genetic and epigenetic aberrations of ABCB1 synergistically boost the acquisition of taxane resistance in esophageal squamous cancer cells - Sumarpo, Anton; Ito, Kazuma; Saiki, Yuriko; Ishizawa, Kota; Wang, Ruobing; Chen, Na; Sunamura, Makoto; Horii, Akira (Biochemical and biophysical research communications, 2020)
Keywords: ABCB1; Antineoplastic Agents - pharmacology; ATP Binding Cassette Transporter, Subfamily B - genetics; Bridged-Ring Compounds - pharmacology; Cell Line, Tumor; cell lines; Drug Resistance, Neoplasm; drug therapy; Epigenesis, Genetic - drug effects; Epigenetics; esophageal neoplasms; Esophageal Neoplasms - drug therapy; Esophageal Neoplasms - genetics; Esophageal squamous cell carcinoma; Esophageal Squamous Cell Carcinoma - drug therapy; Esophageal Squamous Cell Carcinoma - genetics; Gene amplification; Gene Amplification - drug effects; gene expression; Gene Expression Regulation, Neoplastic - drug effects; Humans; methylation; neoplasm cells; Taxane resistance; taxanes; Taxoids - pharmacology; Epigenetics; Taxane resistance; Esophageal squamous cell carcinoma; Gene amplification; ABCB1