Label-free impedimetric glycan biosensor for quantitative evaluation interactions between pathogenic bacteria and mannose

• Published in: Biosensors & bioelectronics Vol. 103; pp. 94 - 98
• Main Authors: Cui, Feiyun, Xu, Yi, Wang, Renjie, Liu, Haitao, Chen, Li, Zhang, Qing, Mu, Xiaojing
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 30.04.2018
• Subjects: bacteria; Bacteria detection; binding capacity; Biosensing Techniques; biosensors; detection limit; diagnostic techniques; Dielectric Spectroscopy; Electrochemical impedance spectroscopy(EIS); electrochemistry; electron transfer; Escherichia coli; Escherichia coli O157 - isolation & purification; Escherichia coli O157 - pathogenicity; fimbriae; Glycan biosensor; Gold - chemistry; hexanols; Hexanols - chemistry; infectious diseases; Interactions between bacteria and glycan; Limit of Detection; mannose; Mannose - chemistry; pathogenicity; pathogens; point-of-care systems; Polysaccharides - chemistry; quantitative analysis; Sulfhydryl Compounds - chemistry; Bacteria detection; Interactions between bacteria and glycan; Electrochemical impedance spectroscopy(EIS); Glycan biosensor

In order to understanding the pathogenic mechanism of infectious diseases, it was important to study the selective recognition and interaction between pathogenic bacteria and host cells. In this paper, a novel electrochemical impedance biosensor was proposed, in which the Man/MUA-MH/Au sensing surfa...