Effects of tetrahydroxy stilbene glycoside derivatives on free radical damage and apoptosis in APP695V717I transgenic mice

• Published in: Redox report : communications in free radical research Vol. 28; no. 1; p. 2259246
• Main Authors: Qian, Jun, Li, Yun, Wang, Yanyun, Ye, Qunying, Luo, Hongbo
• Format: Journal Article
• Language: English
• Published: Taylor & Francis 31.12.2023; Taylor & Francis Group
• Subjects: Alzheimer’s disease; apoptosis; free radical damage; mitochondrial targeting compounds; oxidative stress; tetrahydroxy stilbene glycoside derivatives

Mitochondrial dysfunction leading to overproduction of oxygen free radicals is an important event in the development of Alzheimer's disease. Tetrahydroxy stilbene glycoside (TSG) is one of the main effective components of Polygonum multiflorum and has a certain free radical scavenging effect. W...