Dysbiosis-Induced Secondary Bile Acid Deficiency Promotes Intestinal Inflammation - Sinha, Sidhartha R.; Haileselassie, Yeneneh; Nguyen, Linh P.; Tropini, Carolina; Wang, Min; Becker, Laren S.; Sim, Davis; Jarr, Karolin; Spear, Estelle T.; Singh, Gulshan; Namkoong, Hong; Bittinger, Kyle; et al. (Cell host & microbe, 2020)
Keywords: Adenomatous Polyposis Coli - microbiology; Animals; bile acids; Bile Acids and Salts - metabolism; Bile Acids and Salts - pharmacology; colitis; Colitis - etiology; Colitis - microbiology; Colonic Pouches - microbiology; Disease Models, Animal; dysbiosis; Dysbiosis - complications; Feces - microbiology; Humans; Inflammation - drug therapy; Inflammation - etiology; inflammatory bowel disease; Intestines - drug effects; Intestines - pathology; metabolomics; Metagenome; Mice; Microbiota; pouchitis; Receptors, G-Protein-Coupled - drug effects; Receptors, G-Protein-Coupled - metabolism; Ruminococcus - isolation & purification; Transcriptome; ulcerative colitis; colitis; bile acids; metabolomics; pouchitis; ulcerative colitis; inflammatory bowel disease; dysbiosis